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Graham Ross Selected Research

pertuzumab

6/20165-year analysis of neoadjuvant pertuzumab and trastuzumab in patients with locally advanced, inflammatory, or early-stage HER2-positive breast cancer (NeoSphere): a multicentre, open-label, phase 2 randomised trial.
2/2015Pertuzumab, trastuzumab, and docetaxel in HER2-positive metastatic breast cancer.
11/2014Biomarker analyses in CLEOPATRA: a phase III, placebo-controlled study of pertuzumab in human epidermal growth factor receptor 2-positive, first-line metastatic breast cancer.
10/2014Population pharmacokinetic and covariate analysis of pertuzumab, a HER2-targeted monoclonal antibody, and evaluation of a fixed, non-weight-based dose in patients with a variety of solid tumors.
7/2014Evaluating the predictive value of biomarkers for efficacy outcomes in response to pertuzumab- and trastuzumab-based therapy: an exploratory analysis of the TRYPHAENA study.
7/2014Safety profile of Pertuzumab with Trastuzumab and Docetaxel in patients from Asia with human epidermal growth factor receptor 2-positive metastatic breast cancer: results from the phase III trial CLEOPATRA.
11/2013Treatment of older patients with HER2-positive metastatic breast cancer with pertuzumab, trastuzumab, and docetaxel: subgroup analyses from a randomized, double-blind, placebo-controlled phase III trial (CLEOPATRA).
11/2013Absence of pharmacokinetic drug-drug interaction of pertuzumab with trastuzumab and docetaxel.
5/2013Pertuzumab, trastuzumab, and docetaxel for HER2-positive metastatic breast cancer (CLEOPATRA study): overall survival results from a randomised, double-blind, placebo-controlled, phase 3 study.
1/2013Cardiac tolerability of pertuzumab plus trastuzumab plus docetaxel in patients with HER2-positive metastatic breast cancer in CLEOPATRA: a randomized, double-blind, placebo-controlled phase III study.
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Graham Ross Research Topics

Disease

11Breast Neoplasms (Breast Cancer)
06/2016 - 01/2012
5Neutropenia
06/2016 - 05/2002
3Febrile Neutropenia
06/2016 - 01/2012
3Neoplasms (Cancer)
11/2014 - 05/2002
3Small Cell Lung Carcinoma (Small Cell Lung Cancer)
05/2007 - 08/2005
2Inflammatory Breast Neoplasms
06/2016 - 01/2012
2Body Weight (Weight, Body)
10/2014 - 05/2002
2Left Ventricular Dysfunction
01/2013 - 01/2012
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
11/2012 - 06/2006
2Anemia
05/2007 - 06/2006
2Thrombocytopenia (Thrombopenia)
05/2007 - 06/2006
1Suppuration
02/2020
1Cellulitis
05/2013
1Pneumonia (Pneumonitis)
05/2013
1Diarrhea
01/2012
1Disease Progression
01/2012
1Sepsis (Septicemia)
05/2007

Drug/Important Bio-Agent (IBA)

13pertuzumabIBA
06/2016 - 01/2012
11Docetaxel (Taxotere)FDA Link
06/2016 - 06/2006
11Trastuzumab (Herceptin)FDA Link
06/2016 - 01/2012
6human ERBB2 proteinIBA
02/2015 - 01/2012
5Topotecan (Hycamtin)FDA LinkGeneric
05/2007 - 05/2002
2Biomarkers (Surrogate Marker)IBA
02/2020 - 11/2014
2ErbB Receptors (EGF Receptor)IBA
11/2014 - 07/2014
2Monoclonal AntibodiesIBA
10/2014 - 01/2012
2Cisplatin (Platino)FDA LinkGeneric
05/2006 - 08/2005
2Etoposide (VP 16)FDA LinkGeneric
05/2006 - 08/2005
1antineoplaston A10 (A 10)IBA
06/2016
1Indicators and Reagents (Reagents)IBA
06/2016
1Progesterone Receptors (Progesterone Receptor)IBA
06/2016
1Drug CombinationsIBA
02/2015
1BetacellulinIBA
11/2014
1Insulin-Like PeptidesIBA
11/2014
1Epidermal Growth Factor (EGF)IBA
11/2014
1Transforming Growth Factor alpha (TGF-alpha)IBA
11/2014
1AmphiregulinIBA
11/2014
1Serum AlbuminIBA
10/2014
1Biological ProductsIBA
05/2013
1Erlotinib Hydrochloride (CP 358,774)FDA Link
11/2012
1AntibodiesIBA
01/2012
1Hormones (Hormone)IBA
01/2012
1Pharmaceutical PreparationsIBA
01/2012
1PlatinumIBA
05/2002

Therapy/Procedure

7Drug Therapy (Chemotherapy)
02/2015 - 05/2006
5Therapeutics
02/2015 - 05/2007
1Biological Therapy
11/2013